what are the side effects of this pain medication?

what are the side effects of this pain medication?

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Ixprim (tramadol and paracetamol): what are the side effects of this pain medication?

This pain medication should be handled with care. Focus on the side effects and contraindications of Ixprim®.

Ixprim (tramadol and paracetamol): what is this medicine?

The drug Ixprim® is a pain reliever, which means that its main function is to relieve pain. The World Health Organization (WHO) classifies Ixprim® as a “level II analgesic”: this medication is therefore prescribed in case of moderate to severe pain, when this is not relieved by an “analgesic I “like the Doliprane®, Dafalgan®,Aspirin® or theIbuprofen®. The Ixprim® is marketed by the Grünenthal laboratories.

Ixprim: how does it work? The drug Ixprim® works thanks to the association of two analgesic molecules: tramadol (an opiate which acts directly on the perception of pain by the brain) and paracetamol (which prevents the transmission of pain to the brain).

To know. The opiates (such as tramadol or morphine) are substances derived from opium which act on the level of the brain, on the receptors of certain chemical messengers such as those of pain, stress or control of emotions. It should be noted that the body naturally produces opiates: these are the endorphins, the famous “pleasure hormones”!

In pharmacies, Ixprim® is only available on medical prescription. It is found in two forms: yellow tablets (20 tablets in a box) and effervescent tablets with orange flavor (20 tablets in a box).

When to take Ixprim (tramadol and paracetamol)?

It has been said: Ixprim® is indicated for the symptomatic treatment of moderate to severe pain. In particular, this medicine can be prescribed in case of:

To know. The Ixprim® is reserved for adults and adolescents from 12 years old. The medical prescription (which is essential: the drug is not sold over the counter) is limited to 12 weeks. As a rule, the drug Ixprim® should be taken for the shortest possible time.

Ixprim: instructions for use. Of course, it is necessary to follow the doctor’s instructions regarding the dosage of the drug. In adults and adolescents after 12 years, the usual dosage is 2 tablets to be renewed if necessary, respecting a minimum interval of 6 hours between doses. And you should never exceed 8 tablets per day!

Warning ! The drug Ixprim® can cause drowsiness. Because taking alcohol can make drowsiness worse, it is best not to drink alcohol for the duration of treatment.

Is it dangerous to take Ixprim (tramadol and paracetamol)?

What are the contraindications for Ixprim? They are many. First, it is strictly forbidden to take Ixprim® in the event of:

  • Allergy to paracetamol or tramadol,
  • Alcohol intoxication or intoxication with sleeping pills, other pain medications or psychotropic drugs (drugs that affect mood and emotions),
  • Treatment based on Monoamine Oxidase Inhibitors (MAOIs): in case of drug treatment with Marsilid® against depression, for example,
  • Severe liver disease: cirrhosis, cancer, non-alcoholic steatohepatitis (NASH)…,
  • Epilepsy not controlled by treatment.

Deuzio, it is not recommended to take Ixprim® in the following cases:

  • If you are already taking a treatment with paracetamol or tramadol,
  • If you have liver problems (liver failure, for example),
  • If you have kidney disease (renal failure, for example),
  • If you have respiratory or lung disease (asthma, Sleep Apnea…),
  • If you have epilepsy,
  • If you are taking other pain medications – such as buprenorphine, nalbuphine or pentazocine.

It is therefore necessary to seek advice from your doctor in order to possibly develop a lighter and more suitable dosage.

Can I take Ixprim during pregnancy? The Ministry of Health explains that ” due to the presence of tramadol, Ixprim® should not be used during pregnancy or breastfeeding. If you discover that you are pregnant during treatment, consult your doctor before taking the next tablets. Tramadol is excreted in breast milk. For this reason, Ixprim® should not be taken more than once during breastfeeding. If you take Ixprim® repeatedly, you should stop breastfeeding your child.

What are the possible side effects of Ixprim? Again, the list is long. During treatment with Ixprim®, the following side effects may be observed:

  • Very frequently (in more than 10% of patients): nausea, drowsiness, dizziness.
  • Frequently (in 1% to 10% of patients): vomiting, constipation, diarrhea, dry mouth, abdominal pain, difficult digestion, bloating, headache, tremors, anxiety, nervousness, euphoria, sleep disturbances, sweating, itching.
  • Uncommon (0.1% to 1% of patients): ringing in the ears, depression, hallucinations, nightmares, tingling, high blood pressure, malaise, palpitations, shortness of breath, difficulty urinating, chills, chest pain, flushing heat, rashes.
  • Rarely (in less than 0.1% of patients): blurred vision, convulsions, difficulty coordinating movement, malaise, speech impairment, delirium, potentially severe rashes.

To know. Because it contains an opiate substance, Ixprim® can cause dependence in case of prolonged use and / or high doses. This risk of dependence is increased in people who have previously been addicted to other medicines or other substances. Suddenly stopping treatment can therefore lead to a “withdrawal syndrome” characterized by panic attacks, severe anxiety, hallucinations or tingling in the extremities.

And also. While driving, this medicine may be responsible for dizziness or decreased alertness.

What are the generic drugs of Ixprim? Among the generic drugs of Ixprim®, mention may in particular be made of Zaldiar® and Tramadol / Paracetamol®.


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