These are remdesivir, hydroxychloroquine, lopinavir, and interferon.
Four drugs that were being tested by one of the largest clinical trials led by the World Health Organization would not be effective against the coronavirus. (Read: WHO launches “Solidarity”, an international clinical study to combat the coronavirus)
According to the preliminary study published in the journal MedRxviv, reused antivirals for covid-19 – remdesivir, hydroxychloroquine, lopinavir, and interferonhave little or even no clinical effect.
The Solidaridad clinical study, as it was baptized, is being developed in 30 countries, including Colombia, and seeks to share research on covid-19 that is being carried out simultaneously in different countries. In the case of the four antivirals, they were 11,266 volunteers who, for about 15 days, were given a controlled dose of these drugs.
“In 405 hospitals in 30 countries, 11,266 adults were randomized, with 2,750 given remdesivir, 954 hydroxychloroquine, 1,411 lopinavir, 651 interferon plus lopinavir, 1,412 interferon only, and 4,088 no medication,” the study explains.
It further concludes that “these regimens of remdesivir, hydroxychloroquine, lopinavir and interferon appeared to have little or no effect.